testosterone


EMA43



General information:


Withdrawn ID: EMA43
Canonical SMILES:
Standard InChI:
Standard InChIKey:
ATC class(es): G03BA03
Molecular Formula: C19H28O2
Molweight: 288.424



Withdrawal information:


Withdrawn due to drug safety reasons:No



Side-effects:

Total reported cases (submitted by medical professionals) with testosterone as primary suspect: 11187


Reported final outcomes:
Hospitalization (initial or prolonged): 2976
Disability: 865
Death: 712
Life-Threatening condition: 213
Intervention required to prevent permanent impairment/damage: 14
Congenital anomaly: 1


Reported side-effects:

Side-effect Case number
MYOCARDIAL INFARCTION2784
DEEP VEIN THROMBOSIS1777
CEREBROVASCULAR ACCIDENT1679
PULMONARY EMBOLISM1570
PAIN1148
Economic problem1054
INJURY884
ACUTE MYOCARDIAL INFARCTION714
Emotional distress706
ANXIETY664
THROMBOSIS612
Anhedonia426
Impaired work ability410
CORONARY ARTERY DISEASE375
BLOOD TESTOSTERONE DECREASED366
Physical disability364
FEAR322
DRUG INEFFECTIVE308
Social problem297
TRANSIENT ISCHAEMIC ATTACK263
Cardiovascular disorder227
Emotional disorder211
DEATH208
CHEST PAIN199
ATRIAL FIBRILLATION184
CARDIAC FAILURE CONGESTIVE178
FATIGUE160
ASTHENIA160
OFF LABEL USE155
BLOOD TESTOSTERONE INCREASED155
INCORRECT DOSE ADMINISTERED152
CARDIAC ARREST147
Loss of employment144
HYPERTENSION133
DYSPNOEA132
Ischaemic stroke128
POLYCYTHAEMIA121
CARDIAC DISORDER109
DEPRESSION108
DRUG ABUSE106
HEADACHE104
Prescribed overdose96
RASH93
Cerebral infarction85
PNEUMONIA83
PRODUCT QUALITY ISSUE81
PROSTATE CANCER77
OSTEONECROSIS75
DIZZINESS75
CARDIAC FAILURE74
NAUSEA73
Accidental exposure to product69
MULTIPLE INJURIES66
APPLICATION SITE RASH66
LUNG DISORDER63
ANGINA PECTORIS63
PAIN IN EXTREMITY62
Idiopathic intracranial hypertension61
Acute kidney injury61
Product deposit59
DRUG ADMINISTERED AT INAPPROPRIATE SITE59
PROSTATIC SPECIFIC ANTIGEN INCREASED57
FALL55
UNEVALUABLE EVENT54
CARDIOMYOPATHY54
Thrombophlebitis superficial52
HYPERHIDROSIS52
ACUTE CORONARY SYNDROME52
OEDEMA PERIPHERAL51
AMNESIA51
Wrong technique in product usage process50
Cardio-respiratory arrest50
SYNCOPE49
SLEEP APNOEA SYNDROME49
Tension48
HAEMATOCRIT INCREASED48
WEIGHT INCREASED47
APPLICATION SITE ERYTHEMA47
Heart injury46
Application site pain46
ACNE46
Quality of life decreased45
Disability44
RESPIRATORY FAILURE43
PRECOCIOUS PUBERTY43
INSOMNIA43
GAIT DISTURBANCE43
BLOOD TESTOSTERONE ABNORMAL43
AGGRESSION43
ISCHAEMIC CARDIOMYOPATHY42
CORONARY ARTERY OCCLUSION42
PRURITUS41
HAIR GROWTH ABNORMAL41
PULMONARY INFARCTION40
Acute respiratory failure40
ACCIDENTAL EXPOSURE40
Product storage error39
HYPERLIPIDAEMIA39
Angina unstable39
ANAEMIA39
PALPITATIONS38
Myocardial ischaemia38
DRUG DOSE OMISSION38
HYPOAESTHESIA37
Expulsion of medication37
Arteriosclerosis coronary artery37
ARRHYTHMIA37
Peripheral swelling36
MESENTERIC VEIN THROMBOSIS36
MALAISE36
LIBIDO DECREASED36
LACUNAR INFARCTION36
ERECTILE DYSFUNCTION36
ARTHRALGIA36
Seizure35
OVERDOSE35
HYPERSENSITIVITY35
BACK PAIN35
Partner stress34
GYNAECOMASTIA34
General physical health deterioration34
Cardiogenic shock34
BLOOD PRESSURE INCREASED34
APPLICATION SITE PRURITUS34
VOMITING33
Ventricular fibrillation33
RENAL FAILURE33
PLEURAL EFFUSION33
CONDITION AGGRAVATED33
Arteriosclerosis33
FEELING ABNORMAL32
DIABETES MELLITUS32
CELLULITIS32
BALANCE DISORDER32
AORTIC ANEURYSM32
ABDOMINAL PAIN32
WEIGHT DECREASED31
PRODUCT ODOUR ABNORMAL31
NO ADVERSE EVENT31
MYALGIA31
IRRITABILITY31
HYPOTENSION31
HEART RATE IRREGULAR31
ERYTHEMA31
PULMONARY HYPERTENSION30
MUSCULAR WEAKNESS29
Intentional product misuse29
IMPLANT SITE PAIN29
BRADYCARDIA29
DRUG INTERACTION28
DRUG ADMINISTRATION ERROR28
CHEST DISCOMFORT28
LOSS OF CONSCIOUSNESS27
Embolism27
CORONARY ARTERY THROMBOSIS27
CORONARY ARTERY STENOSIS27
VISUAL IMPAIRMENT26
SUICIDAL IDEATION26
MENTAL DISORDER26
DIARRHOEA26
ARTERIAL OCCLUSIVE DISEASE26
ALOPECIA26
VENTRICULAR TACHYCARDIA25
Underdose25
SEPSIS25
Pulmonary oedema25
PORTAL VEIN THROMBOSIS25
Peripheral vascular disorder25
PANCREATITIS25
HEMIPARESIS25
CARDIOMEGALY25
APPLICATION SITE REACTION25
ANGER25
Retinal vein occlusion24
Product administered at inappropriate site24
Nervous system disorder24
Intracardiac thrombus24
CIRCUMSTANCE OR INFORMATION CAPABLE OF LEADING TO MEDICATION ERROR24
TESTICULAR ATROPHY23
Sudden cardiac death23
SKIN IRRITATION23
PYREXIA23
Product use issue23
Musculoskeletal pain23
Inappropriate schedule of drug administration23
Coronary artery bypass23
TACHYCARDIA22
MUSCLE SPASMS22
MEMORY IMPAIRMENT22
LEFT VENTRICULAR HYPERTROPHY22
JOINT SWELLING22
Infarction22
Implant site infection22
HAEMOGLOBIN INCREASED22
Cerebrovascular disorder22
Cerebellar infarction22
Carotid artery stenosis22
BLINDNESS22
Angiopathy22
Retinal artery occlusion21
Renal infarct21
Papilloedema21
INFERTILITY21
Embolic stroke21
CEREBRAL HAEMORRHAGE21
VIRILISM20
Intracranial pressure increased20
Haemorrhagic stroke20
CONFUSIONAL STATE20
Cognitive disorder20
Brain injury20
APPLICATION SITE IRRITATION20
Venous thrombosis19
Speech disorder19
NEUROPATHY PERIPHERAL19
Multiple use of single-use product19
MITRAL VALVE INCOMPETENCE19
Laceration19
INCORRECT ROUTE OF DRUG ADMINISTRATION19
Embolism venous19
DRUG EFFECT DECREASED19
CHORIORETINOPATHY19
BURNING SENSATION19
TYPE 2 DIABETES MELLITUS18
THERAPEUTIC RESPONSE UNEXPECTED18
PRODUCT PHYSICAL ISSUE18
MENTAL STATUS CHANGES18
Left ventricular dysfunction18
AZOOSPERMIA18
APPLICATION SITE VESICLES18
Accidental exposure to product by child18
Treatment noncompliance17
Toxicity to various agents17
RASH PRURITIC17
Product physical consistency issue17
Product container issue17
MOOD SWINGS17
HEART RATE INCREASED17
Family stress17
DYSPHAGIA17
DYSARTHRIA17
Drug-induced liver injury17
Congestive cardiomyopathy17
Chronic obstructive pulmonary disease17
BLOOD GLUCOSE INCREASED17
ATRIAL FLUTTER17
PROSTATOMEGALY16
POOR QUALITY DRUG ADMINISTERED16
PARAESTHESIA16
OEDEMA16
Mental impairment16
MEDICATION ERROR16
HOT FLUSH16
ENLARGED CLITORIS16
Coagulopathy16
Atelectasis16
ARTHROPATHY16
APHASIA16
Aortic valve incompetence16
VERTIGO15
URTICARIA15
THROMBOPHLEBITIS15
SWELLING15
ROAD TRAFFIC ACCIDENT15
Optic ischaemic neuropathy15
MOBILITY DECREASED15
LOSS OF LIBIDO15
HYPERCOAGULATION15
DYSURIA15
COUGH15
CORONARY ARTERIAL STENT INSERTION15
Contusion15
BREAST CANCER15
ABDOMINAL PAIN UPPER15
VISION BLURRED14
TREMOR14
Tinnitus14
STAPHYLOCOCCAL INFECTION14
SINUS TACHYCARDIA14
Sexual relationship change14
Product use in unapproved indication14
Product dispensing error14
NEPHROLITHIASIS14
Injection site pain14
INFERTILITY MALE14
Hypoxic-ischaemic encephalopathy14
Hypertensive heart disease14
Hepatocellular carcinoma14
Gastrointestinal haemorrhage14
Catheterisation cardiac14
Carotid artery occlusion14
Bronchitis14
BENIGN PROSTATIC HYPERPLASIA14
ROTATOR CUFF SYNDROME13
RHINORRHOEA13
Product administration error13
Peripheral arterial occlusive disease13
MOOD ALTERED13
Ischaemic cerebral infarction13
HAEMATURIA13
GASTROOESOPHAGEAL REFLUX DISEASE13
DRUG PRESCRIBING ERROR13
DISTURBANCE IN ATTENTION13
Constipation13
Chronic kidney disease13
Brain stem infarction13
AGITATION13
SOMNOLENCE12
POLLAKIURIA12
Peripheral venous disease12
MIGRAINE12
LIBIDO INCREASED12
HEPATIC ENZYME INCREASED12
Epistaxis12
DYSGEUSIA12
Coma12
BREAST TENDERNESS12
BLOOD TESTOSTERONE FREE DECREASED12
BLOOD CHOLESTEROL INCREASED12
Blindness unilateral12
ASTHMA12
APPLICATION SITE EXFOLIATION12
APPLICATION SITE DISCOLOURATION12
Aneurysm12
URINARY TRACT INFECTION11
Thrombocytopenia11
Thalamic infarction11
Surgery11
Stress11
SLEEP DISORDER11
Septic shock11
RED BLOOD CELL COUNT INCREASED11
Product delivery mechanism issue11
PRIAPISM11
Metaplasia11
Large intestine polyp11
Ischaemia11
Invasive ductal breast carcinoma11
INFECTION11
Hypokalaemia11
HYPOGONADISM11
HIRSUTISM11
HAEMORRHAGE11
Expired product administered11
Device expulsion11
DERMATITIS CONTACT11
DEHYDRATION11
CHOLELITHIASIS11
APPLICATION SITE DRYNESS11
ABNORMAL BEHAVIOUR11
VENTRICULAR HYPOKINESIA10
URINARY RETENTION10
UPPER RESPIRATORY TRACT INFECTION10
SKIN ODOUR ABNORMAL10
SKIN EXFOLIATION10
SINUSITIS10
SEXUAL DYSFUNCTION10
PSYCHOTIC DISORDER10
PRODUCT SUBSTITUTION ISSUE10
Product dose omission10
Product adhesion issue10
Poor quality product administered10
PNEUMONIA ASPIRATION10
Peripheral artery thrombosis10
Pericarditis10
Osteoarthritis10
NIPPLE PAIN10
Limb discomfort10
Intermittent claudication10
Hypoxia10
HEPATIC STEATOSIS10
HEPATIC FUNCTION ABNORMAL10
DRUG HYPERSENSITIVITY10
DRUG DEPENDENCE10
Disease susceptibility10
Diastolic dysfunction10
DECREASED APPETITE10
CRYING10
Cardiac failure acute10
Cardiac death10
ARTHRITIS10
AMAUROSIS FUGAX10
Affect lability10
Abdominal distension10
Abdominal discomfort10
VISUAL FIELD DEFECT9
VISUAL ACUITY REDUCED9
VENTRICULAR EXTRASYSTOLES9
TESTICULAR PAIN9
Subarachnoid haemorrhage9
SKIN REACTION9
RASH ERYTHEMATOUS9
PROSTATITIS9
Product packaging quantity issue9
Pericardial effusion9
NO THERAPEUTIC RESPONSE9
Night sweats9
Nerve injury9
NECK PAIN9
MUSCLE MASS9
Local swelling9
Leukocytosis9
Lethargy9
Intracranial aneurysm9
Incorrect product storage9
Inappropriate schedule of product administration9
Implant site swelling9
Implant site bruising9
Hyponatraemia9
HYPERGLYCAEMIA9
HEAD INJURY9
FLUSHING9
Essential hypertension9
Endocarditis9
Dyslipidaemia9
Drug-disease interaction9
Drug level increased9
Device issue9
Deformity9
Coronary bypass thrombosis9
Cerebral disorder9
Cerebral artery occlusion9
Basal ganglia infarction9
APPLICATION SITE URTICARIA9
URINARY INCONTINENCE8
Transaminases increased8
TENDON RUPTURE8
SKIN DISCOLOURATION8
RHABDOMYOLYSIS8
RESPIRATORY DISORDER8
RESPIRATORY ARREST8
RASH GENERALISED8
Pulmonary mass8
Presyncope8
OESTRADIOL INCREASED8
Obesity8
NERVOUSNESS8
NEOPLASM MALIGNANT8
Nasal discomfort8
MANIA8
LUNG NEOPLASM MALIGNANT8
LOW DENSITY LIPOPROTEIN INCREASED8
Loss of personal independence in daily activities8
LIQUID PRODUCT PHYSICAL ISSUE8
Intraductal proliferative breast lesion8
Intentional product use issue8
Implant site haemorrhage8
Implant site erythema8
Hypogonadism male8
HYPERTENSIVE CRISIS8
Hemiplegia8
Haemorrhoids8
Gout8
Encephalopathy8
EJECTION FRACTION DECREASED8
DYSPHONIA8
DRY SKIN8
DRUG DISPENSING ERROR8
Discomfort8
Device dislocation8
Depressed mood8
Cardiac ventricular thrombosis8
Cardiac pacemaker insertion8
Bundle branch block right8
BLOOD CREATININE INCREASED8
Arterial thrombosis8
ANGIOEDEMA8
ALANINE AMINOTRANSFERASE INCREASED8
AFFECTIVE DISORDER8
WOUND7
Venous thrombosis limb7
Vaginal disorder7
Supraventricular tachycardia7
Stent placement7
Spinal cord abscess7
SLUGGISHNESS7
Skin lesion7
Skin laceration7
SINUS BRADYCARDIA7
RENAL IMPAIRMENT7
Renal artery thrombosis7
PULMONARY THROMBOSIS7
Proteinuria7
PHARMACEUTICAL PRODUCT COMPLAINT7
Peripheral ischaemia7
Peripheral artery occlusion7
Panic attack7
Non-cardiac chest pain7
NOCTURIA7
MUSCLE ATROPHY7
Multiple organ dysfunction syndrome7
LEFT VENTRICULAR FAILURE7
LABORATORY TEST ABNORMAL7
INTERVERTEBRAL DISC DEGENERATION7
INFLAMMATION7
Hypokinesia7
HYPERTRICHOSIS7
Hyperthyroidism7
Hypercholesterolaemia7
Hydronephrosis7
Hospitalisation7
HERNIA7
Haemorrhage intracranial7
HAEMOPTYSIS7
Facial paralysis7
EUPHORIC MOOD7
Diplopia7
Device malfunction7
DERMATITIS7
DELIRIUM7
CEREBRAL VENOUS THROMBOSIS7
Cerebral thrombosis7
CEREBRAL ISCHAEMIA7
CATARACT7
Carotid arteriosclerosis7
BREAST PAIN7
BLISTER7
Atrial thrombosis7
Ataxia7
ASCITES7
APPLICATION SITE BURN7
Aortic stenosis7
Aortic dissection7
ANAPHYLACTIC REACTION7
Adverse event7
Acute left ventricular failure7
WHITE BLOOD CELL COUNT INCREASED6
VENTRICULAR HYPERTROPHY6
VENTRICULAR DYSFUNCTION6
Vein disorder6
Vascular pseudoaneurysm6
URINARY HESITATION6
Tricuspid valve incompetence6
Therapy cessation6
THERAPEUTIC RESPONSE DECREASED6
SUICIDE ATTEMPT6
Spinal cord compression6
SPERM CONCENTRATION DECREASED6
Self-destructive behaviour6
SCAR6
RIB FRACTURE6
Pulmonary fibrosis6
PHLEBITIS SUPERFICIAL6
PHLEBITIS6
Peripheral embolism6
Performance enhancing product use6
PENIS DISORDER6
Parkinson's disease6
Obstructive sleep apnoea syndrome6
NIGHTMARE6
Nephropathy6
Nasal dryness6
Myocardial fibrosis6
Musculoskeletal chest pain6
Metastases to lung6
Lymphadenopathy6
LIMB INJURY6
Life expectancy shortened6
LACRIMATION INCREASED6
Injection site swelling6
INCREASED APPETITE6
Hypothyroidism6
HYPOGLYCAEMIA6
Hyperoestrogenism6
Haemorrhagic anaemia6
Haematoma6
GENERALISED OEDEMA6
Exposure via skin contact6
ENERGY INCREASED6
Endometrial cancer6
DYSPNOEA EXERTIONAL6
DRUG INTOLERANCE6
Diverticulitis6
DILATATION VENTRICULAR6
Device defective6
COMPLETED SUICIDE6
Cholangiocarcinoma6
Cardiotoxicity6
Cardiac tamponade6
Breast mass6
Brain stem stroke6
Brain oedema6
Blood testosterone free increased6
ATRIOVENTRICULAR BLOCK FIRST DEGREE6
APPLICATION SITE SWELLING6
Application site inflammation6
APPLICATION SITE DERMATITIS6
Adverse drug reaction6
Activities of daily living impaired6
Venous occlusion5
Vena cava thrombosis5
Vascular injury5
Vascular graft5
Unresponsive to stimuli5
Troponin increased5
Thrombocytosis5
Therapeutic product effect decreased5
Testis cancer5
Testicular disorder5
Superior sagittal sinus thrombosis5
SUDDEN DEATH5
Spinal operation5
Skin disorder5
Skin burning sensation5
Sinus disorder5
Silent myocardial infarction5
SELF-MEDICATION5
RESTLESSNESS5
Restless legs syndrome5
RENAL DISORDER5
PRURITUS GENERALISED5
Product label issue5
Product gel formation5
Product contamination physical5
PLEURISY5
Pharyngitis5
Pelvic venous thrombosis5
Osteoporosis5
Orthostatic hypotension5
Neurological symptom5
MUSCLE HYPERTROPHY5
Meniscus injury5
Medical observation5
Malignant hypertension5
MALABSORPTION5
Liver function test abnormal5
Leg amputation5
Knee operation5
JOINT INJURY5
JAUNDICE5
Intestinal ischaemia5
Influenza5
Infertility female5
Incision site pain5
Impaired healing5
HYPERKALAEMIA5
Hyperbilirubinaemia5
Hydrocephalus5
HOSTILITY5
HORMONE LEVEL ABNORMAL5
HOMICIDAL IDEATION5
Hip arthroplasty5
Hepatitis toxic5
Glycosylated haemoglobin increased5
Flank pain5
FEELING HOT5
Eye irritation5
Endometrial hyperplasia5
Embolism arterial5
Device delivery system issue5
CYST5
Coronary artery restenosis5
CHOLESTASIS5
CHILLS5
Cardiopulmonary failure5
Cardiac valve disease5
CARDIAC OPERATION5
Bundle branch block left5
BREAST CANCER MALE5
Bradyphrenia5
BONE PAIN5
BLOOD LUTEINISING HORMONE DECREASED5
BLOOD FOLLICLE STIMULATING HORMONE DECREASED5
BIPOLAR DISORDER5
BACK DISORDER5
ANGIOFIBROMA5
Acute pulmonary oedema5
ACCELERATED HYPERTENSION5
ABORTION SPONTANEOUS5
WOUND SECRETION4
Wound dehiscence4
Withdrawal syndrome4
WHEEZING4
Walking aid user4
VIIth nerve paralysis4
Vertigo positional4
Vertebral artery dissection4
Vascular stent stenosis4
Varicose vein4
URINE ALCOHOL TEST POSITIVE4
Tracheobronchitis4
SWELLING FACE4
Spinal fusion surgery4
Skin infection4
Skin hypertrophy4
Shoulder operation4
Serotonin syndrome4
SCROTAL OEDEMA4
Rhythm idioventricular4
RHEUMATOID ARTHRITIS4
Retinal neovascularisation4
Retinal detachment4
RENAL FAILURE ACUTE4
RENAL CANCER4
Rash macular4
PULMONARY HAEMORRHAGE4
PULMONARY CONGESTION4
Psychomotor hyperactivity4
PROSTATE CANCER METASTATIC4
Product prescribing error4
PRODUCT PACKAGING ISSUE4
Product label confusion4
Product contamination microbial4
PRODUCT CONTAMINATION4
Procedural complication4
Prescription drug used without a prescription4
POST PROCEDURAL COMPLICATION4
Polycythaemia vera4
Pneumonitis4
PITUITARY TUMOUR BENIGN4
PERSONALITY CHANGE4
Pericardial haemorrhage4
Paralysis4
Overweight4
Osteopenia4
Osteonecrosis of jaw4
ORAL CANDIDIASIS4
Neuralgia4
NEPHROTIC SYNDROME4
NEOPLASM4
Muscle tightness4
MICTURITION URGENCY4
Metastases to peritoneum4
MASS4
Knee arthroplasty4
Irritable bowel syndrome4
INTERVERTEBRAL DISC PROTRUSION4
INTERNATIONAL NORMALISED RATIO INCREASED4
INJECTION SITE REACTION4
Implant site rash4
Implant site mass4
Implant site extravasation4
Ileus4
HYPOTHALAMO-PITUITARY DISORDER4
Hypertrophic cardiomyopathy4
Hypertensive emergency4
Hidradenitis4
HEPATIC ADENOMA4
Heart rate abnormal4
HALLUCINATION4
Haemorrhagic transformation stroke4
Haemorrhagic infarction4
Haematospermia4
GASTROINTESTINAL DISORDER4
Gastroenteritis4
GASTRITIS4
Gastric ulcer4
Frustration4
Focal segmental glomerulosclerosis4
FLUID RETENTION4
Fluid overload4
FACTOR V LEIDEN MUTATION4
Eye disorder4
Exostosis4
Exercise tolerance decreased4
ELECTROCARDIOGRAM ABNORMAL4
Ejaculation failure4
EJACULATION DISORDER4
Eczema4
Drug level below therapeutic4
Drug effect incomplete4
Dressler's syndrome4
DISORIENTATION4
DISEASE RECURRENCE4
Device extrusion4
Dermal absorption impaired4
DEMENTIA4
Deafness4
COORDINATION ABNORMAL4
CONJUNCTIVITIS4
Compartment syndrome4
Clostridium difficile infection4
Clostridium difficile colitis4
CIRCULATORY COLLAPSE4
CHROMATURIA4
Cervix carcinoma stage IV4
Carpal tunnel syndrome4
Carotid artery thrombosis4
Cardiac murmur4
Cardiac aneurysm4
Breast enlargement4
BONE DISORDER4
BLOOD TRIGLYCERIDES INCREASED4
BLOOD PROLACTIN INCREASED4
BLOOD PRESSURE DECREASED4
Blood oestrogen increased4
BLOOD CREATINE PHOSPHOKINASE INCREASED4
Bladder cancer4
ASPARTATE AMINOTRANSFERASE INCREASED4
Application site paraesthesia4
Apathy4
Aortic arteriosclerosis4
Anxiety disorder4
Anaemia postoperative4
Adrenal insufficiency4
ADENOCARCINOMA4
Acne fulminans4
Accidental overdose4
Abscess4
Abnormal weight gain4
Wrong technique in drug usage process3
Wound haemorrhage3
WHITE BLOOD CELL COUNT DECREASED3
Vitamin D decreased3
Vertebral artery occlusion3
VASODILATATION3
Vascular stent thrombosis3
Vascular occlusion3
Uterine cervical metaplasia3
URINE FLOW DECREASED3
Upper gastrointestinal haemorrhage3
Tubulointerstitial nephritis3
THYROID DISORDER3
THYROID CANCER3
Throat tightness3
Therapy non-responder3
Therapy change3
Testis discomfort3
SWOLLEN TONGUE3
Substance use3
SUBDURAL HAEMATOMA3
Subclavian vein thrombosis3
Subclavian artery stenosis3
Streptococcal sepsis3
Streptococcal infection3
Stenosis3
SPINAL DISORDER3
Spinal cord infarction3
SPERM CONCENTRATION ZERO3
Small intestinal obstruction3
SKIN ULCER3
SKIN CANCER3
Secondary hypogonadism3
SCROTAL SWELLING3
SCROTAL PAIN3
Schizophrenia3
RETINAL DISORDER3
Respiratory distress3
Rectal haemorrhage3
PURPURA3
Pulmonary valve incompetence3
Psychiatric symptom3
Psoriasis3
Product use complaint3
Product packaging difficult to open3
Product dose omission issue3
POSTOPERATIVE WOUND INFECTION3
Post-traumatic stress disorder3
Post thrombotic syndrome3
POLYURIA3
Pneumothorax3
PLEURITIC PAIN3
Plasma cell myeloma3
PITUITARY TUMOUR3
Peripheral artery aneurysm3
PENILE SIZE REDUCED3
Partial seizures3
Parosmia3
Paraesthesia oral3
PALLOR3
Otitis media3
Oropharyngeal pain3
Ophthalmic vein thrombosis3
OESTRONE INCREASED3
Nephroangiosclerosis3
NASOPHARYNGITIS3
Musculoskeletal stiffness3
MUSCULOSKELETAL DISCOMFORT3
MUSCLE DISORDER3
MOVEMENT DISORDER3
Motor dysfunction3
Mixed liver injury3
Microcytosis3
Metastasis3
METASTASES TO LYMPH NODES3
METABOLIC ACIDOSIS3
MESENTERIC VASCULAR INSUFFICIENCY3
Mesenteric artery thrombosis3
MENSTRUATION IRREGULAR3
Marital problem3
Malignant melanoma3
Major depression3
LUNG CYST3
LOCALISED INFECTION3
Liver injury3
Lip swelling3
Libido disorder3
Judgement impaired3
Joint dislocation3
Job dissatisfaction3
Jaundice cholestatic3
Ischaemic hepatitis3
Intracranial venous sinus thrombosis3
Intervertebral discitis3
INTERSTITIAL LUNG DISEASE3
Intentional overdose3
INTENTIONAL DRUG MISUSE3
Inguinal hernia3
Influenza like illness3
Incorrect product administration duration3
Impulsive behaviour3
IMPLANT SITE REACTION3
Implant site discharge3
Implant site cellulitis3
Impaired gastric emptying3
ILL-DEFINED DISORDER3
ILEUS PARALYTIC3
IDIOPATHIC THROMBOCYTOPENIC PURPURA3
HYPOVOLAEMIA3
Hypotonia3
HYPOMAGNESAEMIA3
HYPERVISCOSITY SYNDROME3
HYPERVENTILATION3
Hypersomnia3
Hyperaesthesia3
Homicide3
HIGH DENSITY LIPOPROTEIN DECREASED3
Hiatus hernia3
Hepatomegaly3
HEPATITIS CHOLESTATIC3
Hepatic neoplasm3
Heparin-induced thrombocytopenia3
Heart rate decreased3
Hair texture abnormal3
HAEMANGIOMA3
GROWTH ACCELERATED3
Glomerulosclerosis3
GLOMERULONEPHRITIS3
Gerstmann's syndrome3
GENITAL DISORDER MALE3
Generalised tonic-clonic seizure3
General physical condition abnormal3
Gender dysphoria3
GANGRENE3
Gallbladder disorder3
Fibromyalgia3
Feeling jittery3
Fear of disease3
FAECES DISCOLOURED3
Eye pruritus3
EYE PAIN3
Eye movement disorder3
EXPOSURE VIA PARTNER3
EPILEPSY3
ENDOMETRIAL CANCER STAGE I3
Electrocardiogram ST segment elevation3
Ear pain3
Drug ineffective for unapproved indication3
Diverticulum3
Disease progression3
Diabetic neuropathy3
Diabetes mellitus inadequate control3
DERMATITIS ALLERGIC3
DEPRESSED LEVEL OF CONSCIOUSNESS3
DELUSION3
Decreased activity3
Costovertebral angle tenderness3
Coronary artery embolism3
Cold sweat3
Chronic lymphocytic leukaemia3
Cerebral haematoma3
Cerebral artery thrombosis3
Cerebral artery embolism3
Cerebellar ischaemia3
Central serous chorioretinopathy3
Carotid artery disease3
Cardiac failure chronic3
BURNS SECOND DEGREE3
Breast hyperplasia3
BODY HEIGHT INCREASED3
Blood viscosity increased3
Blood urine present3
BLOOD THYROID STIMULATING HORMONE INCREASED3
Blood pressure inadequately controlled3
BLOOD PRESSURE FLUCTUATION3
Blood pressure abnormal3
BLOOD POTASSIUM INCREASED3
Blood glucose decreased3
BLOOD BILIRUBIN INCREASED3
BLOOD ALKALINE PHOSPHATASE INCREASED3
BLOOD ALCOHOL INCREASED3
Basal ganglia haemorrhage3
Attention deficit/hyperactivity disorder3
ATRIOVENTRICULAR BLOCK SECOND DEGREE3
Atrioventricular block3
Atrial tachycardia3
ASPIRATION3
Arterial stenosis3
APPLICATION SITE SCAR3
Aortic thrombosis3
Aortic dilatation3
Androgen deficiency3
Acute sinusitis3
Acne conglobata3
Acidosis3
Accident3
Wrong technique in device usage process2
Wrist fracture2
White matter lesion2
Wheelchair user2
Vitreous haemorrhage2
Vitamin B12 decreased2
VISUAL DISTURBANCE2
Violence-related symptom2
Vertebral foraminal stenosis2
VASCULITIS2
Vascular stent occlusion2
Vascular dementia2
Urogenital haemorrhage2
Urinary tract infection bacterial2
Upper limb fracture2
Unmasking of previously unidentified disease2
Troponin I increased2
TREATMENT FAILURE2
Traumatic lung injury2
Toxic encephalopathy2
Tonsillectomy2
Toe amputation2
Thyroid mass2
Thrombotic stroke2
Throat irritation2
Thoracic vertebral fracture2
THINKING ABNORMAL2
Therapy responder2
Testicular failure2
Terminal insomnia2
Tendonitis2
Tendon injury2
Sunburn2
Substance-induced psychotic disorder2
Substance abuse2
Subdural haemorrhage2
Subcutaneous abscess2
Stress fracture2
Sticky skin2
Steatocystoma multiplex2
Status epilepticus2
Spontaneous cerebrospinal fluid leak syndrome2
Splenic vein thrombosis2
Spinal pain2
Spinal laminectomy2
Spinal artery thrombosis2
Sneezing2
Skin warm2
SKIN MASS2
Skin fissures2
Skin abrasion2
Sinus node dysfunction2
Shoulder arthroplasty2
SEXUAL ABUSE2
Seroma2
Sensory loss2
Sensory disturbance2
Sedation2
Scrotal mass2
SCREAMING2
Sciatica2
RIGHT VENTRICULAR FAILURE2
Right ventricular enlargement2
Right ventricular dysfunction2
Rhinitis allergic2
Retinopathy2
Retinal vascular occlusion2
Retinal artery thrombosis2
RESPIRATORY TRACT INFECTION2
Respiratory tract congestion2
Respiratory rate increased2
RENAL PAIN2
Renal function test abnormal2
RENAL FAILURE CHRONIC2
Renal embolism2
Renal cyst2
Renal cell carcinoma2
RENAL ARTERY STENOSIS2
Renal artery fibromuscular dysplasia2
Recalled product administered2
Recalled product2
Reaction to drug excipients2
Rash maculo-papular2
Rales2
Pyomyositis2
Purulent discharge2
Pulmonary pneumatocele2
Pulmonary arterial hypertension2
Pulmonary alveolar haemorrhage2
Prostatic disorder2
Product residue present2
PRODUCT FORMULATION ISSUE2
Procedural pain2
PRINZMETAL ANGINA2
Prescribed underdose2
Pre-existing condition improved2
Postoperative thoracic procedure complication2
Postinfarction angina2
Post procedural haemorrhage2
Post procedural haematoma2
Poor peripheral circulation2
Polyp2
Platelet count increased2
PERIPHERAL COLDNESS2
Pelvic pain2
Pelvic abscess2
Peliosis hepatis2
Paranoia2
Pancreatitis acute2
Pancreatic neoplasm2
Pancreatic disorder2
PANCREATIC CARCINOMA2
Otitis externa2
Organic erectile dysfunction2
Optic nerve infarction2
Open angle glaucoma2
OESTROGEN RECEPTOR ASSAY POSITIVE2
Oesophagitis2
Ocular hyperaemia2
Occupational exposure to product2
Non-economic loss2
Nocardiosis2
Nipple disorder2
NEOPLASM RECURRENCE2
NEOPLASM PROSTATE2
NECK MASS2
NASAL SEPTUM DEVIATION2
Nasal disorder2
Myositis2
Myopathy2
Myocardial strain2
Myocardial necrosis2
Musculoskeletal disorder2
Muscle spasticity2
Multiple sclerosis2
Multi-organ failure2
MULTI-ORGAN DISORDER2
Mitral valve prolapse2
Middle insomnia2
Microvascular coronary artery disease2
Metabolic syndrome2
Metabolic encephalopathy2
METABOLIC DISORDER2
Meningioma2
Medical diet2
Mastectomy2
Malnutrition2
MALE SEXUAL DYSFUNCTION2
Malabsorption from application site2
Lymphoproliferative disorder2
LYMPHOMA2
Lymphoedema2
Lung infiltration2
LUNG INFECTION2
Logorrhoea2
Localised oedema2
LIVER DISORDER2
Lipohypertrophy2
LIPIDS INCREASED2
LEUKOCYTOCLASTIC VASCULITIS2
Left atrial enlargement2
Left atrial dilatation2
Lactic acidosis2
Klebsiella sepsis2
Joint range of motion decreased2
Iron deficiency anaemia2
Intraocular pressure increased2
Intestinal polyp2
International normalised ratio decreased2
Intercepted medication error2
Intercepted drug administration error2
Intentional product misuse to child2
Injection site pruritus2
Injection site induration2
Injection site erythema2
Injection site cellulitis2
Inferior vena caval occlusion2
Incorrect drug administration duration2
Incorrect dose administered by device2
Incontinence2
Incision site complication2
Inability to afford medication2
IMPRISONMENT2
Implantable defibrillator insertion2
Implant site warmth2
Implant site vesicles2
Implant site necrosis2
Impatience2
Impaired self-care2
Impaired driving ability2
IgA nephropathy2
Hypothalamic pituitary adrenal axis suppression2
Hypopituitarism2
Hypomania2
Hypoaesthesia oral2
Hypoacusis2
Hypervolaemia2
Hyperuricaemia2
Hypertensive urgency2
Hypernatraemia2
Hyperglycaemic hyperosmolar nonketotic syndrome2
Hypercreatininaemia2
HYPERCALCAEMIA2
Hydrocele2
HIP FRACTURE2
Herpes zoster2
HEPATITIS2
Hepatic mass2
HEPATIC FAILURE2
Heart valve incompetence2
Heart disease congenital2
Hamartoma2
Hair disorder2
Hair colour changes2
Haemothorax2
HAEMORRHAGE URINARY TRACT2
Haemoglobin decreased2
Haemochromatosis2
Haematochezia2
Haematemesis2
GROWTH RETARDATION2
Granuloma2
GRANDIOSITY2
GRAND MAL CONVULSION2
Glomerular filtration rate decreased2
Glaucoma2
GINGIVAL PAIN2
GENITAL RASH2
Genital burning sensation2
General symptom2
GENDER IDENTITY DISORDER2
GASTRITIS HAEMORRHAGIC2
Gastric haemorrhage2
Fungal infection2
Functional gastrointestinal disorder2
FOREIGN BODY REACTION2
Foreign body2
Foot amputation2
Food interaction2
Flatulence2
Fine motor skill dysfunction2
Femoral neck fracture2
Femoral artery occlusion2
Febrile neutropenia2
Failure to thrive2
Faecal incontinence2
Facial paresis2
Extrasystoles2
Extra dose administered2
Exposure via father2
ERYSIPELAS2
EPIPHYSES PREMATURE FUSION2
Epididymitis2
Epididymal cyst2
EOSINOPHILIC MYOCARDITIS2
Endometrial adenocarcinoma2
End stage renal disease2
Embolic cerebral infarction2
Electrocardiogram ST-T segment abnormal2
DYSPHEMIA2
DYSPEPSIA2
Dry mouth2
DRUG WITHDRAWAL SYNDROME2
DRUG SCREEN POSITIVE2
Drug level fluctuating2
Drug level decreased2
Dizziness postural2
Diverticulum intestinal2
Dissociative identity disorder2
Disinhibition2
Disease complication2
DILATATION ATRIAL2
DIHYDROTESTOSTERONE INCREASED2
DIALYSIS2
Diabetic ketoacidosis2
Device related infection2
Device occlusion2
Device ineffective2
DEVICE DIFFICULT TO USE2
Device breakage2
DEVICE ADHESION ISSUE2
DEPRESSION SUICIDAL2
Deafness unilateral2
Deafness neurosensory2
Cushing's syndrome2
Cortisol increased2
Coronary artery dissection2
Coronary angioplasty2
CONVULSION2
Contraindicated product administered2
Colon cancer2
Clumsiness2
Clear cell renal cell carcinoma2
Choroidal effusion2
Choking2
Chloasma2
Cervical radiculopathy2
Cerumen impaction2
Cerebral arteriosclerosis2
Cerebellar stroke2
Cerebellar haemorrhage2
Cardiac valve vegetation2
Cardiac stress test abnormal2
Cardiac hypertrophy2
CARDIAC FLUTTER2
Brugada syndrome2
Breath alcohol test positive2
Brain neoplasm2
BONE DEVELOPMENT ABNORMAL2
BODY TEMPERATURE INCREASED2
BODY HEIGHT ABOVE NORMAL2
Blood urea increased2
Blood pressure systolic increased2
BLOOD PARATHYROID HORMONE DECREASED2
Blood iron decreased2
BLOOD GONADOTROPHIN DECREASED2
Blood disorder2
Blood blister2
Blindness transient2
Basilar artery thrombosis2
Basal ganglia stroke2
Basal cell carcinoma2
Bacteraemia2
Back injury2
Autonomic nervous system imbalance2
Autoimmune disorder2
Atrioventricular block complete2
Atrial septal defect2
Arthropod bite2
APPLICATION SITE HYPERSENSITIVITY2
Appendicitis2
Apocrine breast carcinoma2
Aortic injury2
Aortic embolus2
Anuria2
ANTISOCIAL BEHAVIOUR2
Antiphospholipid syndrome2
Antiphospholipid antibodies positive2
Antiphospholipid antibodies2
Ankylosing spondylitis2
Angle closure glaucoma2
ANDROGENETIC ALOPECIA2
ANAPHYLACTIC SHOCK2
Anal incontinence2
AMENORRHOEA2
Alpha haemolytic streptococcal infection2
Alcohol abuse2
Akathisia2
Ageusia2
Administration site pain2
Actinic keratosis2
Abnormal loss of weight2
Abdominal tenderness2
Abdominal pain lower2
Yawning1
Wrong strength1
Wrong dose1
Wound infection1
Wolff-Parkinson-White syndrome1
West Nile viral infection1
Weight loss poor1
WEIGHT FLUCTUATION1
Weight bearing difficulty1
WAIST CIRCUMFERENCE INCREASED1
VULVOVAGINAL MYCOTIC INFECTION1
Vulvovaginal burning sensation1
VOCAL CORD DISORDER1
Vocal cord atrophy1
VITH NERVE PARALYSIS1
Vitamin D deficiency1
Viral upper respiratory tract infection1
Viral myocarditis1
VIRAL INFECTION1
Victim of sexual abuse1
Vertebral artery thrombosis1
Vertebral artery stenosis1
Ventricular tachyarrhythmia1
Ventricular arrhythmia1
Venous stenosis1
VENOUS INSUFFICIENCY1
Venous injury1
Venomous sting1
Vein collapse1
Vasospasm1
VASOMOTOR RHINITIS1
Vascular stent restenosis1
VASCULAR PURPURA1
Vascular parkinsonism1
Vascular insufficiency1
Vascular graft occlusion1
Vascular graft complication1
Vascular compression1
Vascular calcification1
Varicocele1
Vaginal haemorrhage1
Vaginal discharge1
UTERINE ENLARGEMENT1
URTICARIA CHOLINERGIC1
Urine uric acid increased1
URINE ODOUR ABNORMAL1
Urine electrolytes increased1
Urine analysis abnormal1
Urinary tract obstruction1
Urinary tract infection staphylococcal1
Urinary tract disorder1
URINARY SEDIMENT PRESENT1
Urinary casts1
Ureterolithiasis1
Urea urine increased1
Upper-airway cough syndrome1
Upper respiratory fungal infection1
UMBILICAL HERNIA, OBSTRUCTIVE1
Type V hyperlipidaemia1
Type IIa hyperlipidaemia1
TYPE 1 DIABETES MELLITUS1
Tumour excision1
Tubular breast carcinoma1
Trigger finger1
Transverse sinus thrombosis1
TRANSFUSION REACTION1
Transcription medication error1
Toxic skin eruption1
Toxic cardiomyopathy1
Torticollis1
Tooth loss1
Tooth injury1
TOOTH DISORDER1
Tonsillar neoplasm1
TONGUE ULCERATION1
TONGUE CANCER METASTATIC1
Tic1
Thyroxine free decreased1
Thyroxine decreased1
Thyroid hormones decreased1
Thyroid function test abnormal1
Thrombosis mesenteric vessel1
Thrombosis in device1
Thrombosed varicose vein1
THIRST1
Thermal burn1
Therapeutic response increased1
Therapeutic response changed1
Therapeutic product effect increased1
Testicular mass1
Testicular injury1
Testicular failure primary1
Testicular abscess1
Tendon disorder1
Tendinous contracture1
Temporomandibular joint syndrome1
Temperature intolerance1
Tearfulness1
Tarsal tunnel syndrome1
Tachypnoea1
Tachyphrenia1
TACHYARRHYTHMIA1
TABLET PHYSICAL ISSUE1
T-LYMPHOCYTE COUNT DECREASED1
Systolic dysfunction1
SYSTEMIC CANDIDA1
Syringe issue1
Synovial cyst1
SYNCOPE VASOVAGAL1
Susac's syndrome1
Surgical procedure repeated1
SUPRAVENTRICULAR EXTRASYSTOLES1
Superior vena cava syndrome1
Suicidal behaviour1
Substance use disorder1
Subdiaphragmatic abscess1
Subcutaneous haematoma1
Subclavian artery thrombosis1
Subclavian artery occlusion1
Subacute endocarditis1
Stress cardiomyopathy1
Stress at work1
Strabismus1
Stenotrophomonas infection1
Steal syndrome1
Squamous cell carcinoma of skin1
Squamous cell carcinoma1
Sputum purulent1
Spontaneous penile erection1
Spondylolisthesis1
Splenic thrombosis1
Splenic rupture1
Spinal osteoarthritis1
Spinal fusion acquired1
Spinal fracture1
Spinal decompression1
Spinal cord injury1
Spinal compression fracture1
Spinal column stenosis1
SPINAL COLUMN INJURY1
Spermatozoa progressive motility decreased1
SPERMATOZOA ABNORMAL1
Spasmodic dysphonia1
Soliloquy1
Snoring1
Small cell lung cancer metastatic1
Small cell lung cancer1
SLIPPED FEMORAL EPIPHYSIS1
Sleep terror1
Skin tightness1
Skin striae1
Skin plaque1
Skin papilloma1
Skin injury1
SKIN INFLAMMATION1
SKIN HYPERPIGMENTATION1
SKIN GRAFT1
Skin fragility1
Skin discomfort1
SKIN DESQUAMATION1
SKIN CANDIDA1
Skeletal injury1
Sinus arrhythmia1
Sinus arrest1
Sinobronchitis1
Silent sinus syndrome1
SICK SINUS SYNDROME1
Shock1
SEXUALLY INAPPROPRIATE BEHAVIOUR1
SEX HORMONE BINDING GLOBULIN INCREASED1
Sepsis syndrome1
Sensitisation1
Semen volume decreased1
Semen discolouration1
Self-injurious ideation1
Secondary transmission1
Seborrhoeic keratosis1
Seborrhoea1
Scrotal disorder1
SCROTAL CYST1
Scrotal abscess1
SCOTOMA1
Sciatic nerve injury1
Schwannoma1
Scab1
Ruptured cerebral aneurysm1
ROSACEA1
Right atrial pressure increased1
Right atrial dilatation1
Rhinitis1
Reversible ischaemic neurological deficit1
Retroperitoneal haematoma1
Retroperitoneal fibrosis1
Retinopathy proliferative1
Retinopathy hypertensive1
Retinal vascular thrombosis1
Retinal oedema1
Retinal ischaemia1
Retinal infarction1
Retinal haemorrhage1
Respiratory syncytial virus infection1
Respiratory symptom1
Respiratory acidosis1
Respiration abnormal1
Reperfusion arrhythmia1
RENAL VASCULITIS1
RENAL TUBULAR NECROSIS1
Renal transplant1
Renal neoplasm1
Renal colic1
Renal artery occlusion1
Refraction disorder1
Reflux laryngitis1
RECTAL CANCER STAGE 01
RAYNAUD'S PHENOMENON1
Rash vesicular1
Rash papular1
Radiculopathy1
RADIATION INJURY1
QRS axis abnormal1
Pulmonary vein occlusion1
Pulmonary oil microembolism1
PULMONARY MICROEMBOLI1
Pulmonary artery thrombosis1
Pulmonary arterial pressure increased1
Pterygium1
Psychological trauma1
Pseudostroke1
PROTHROMBIN LEVEL DECREASED1
PROTEIN URINE PRESENT1
Protein S deficiency1
Protein S decreased1
Protein deficiency1
Protein C deficiency1
Prostatic specific antigen decreased1
Prostatic specific antigen abnormal1
Prostatic operation1
Prostatic dysplasia1
PROSTATE CANCER STAGE IV1
PROSTATE CANCER STAGE II1
Prostate cancer recurrent1
Prosopagnosia1
Prolactin-producing pituitary tumour1
PROGESTERONE RECEPTOR ASSAY POSITIVE1
Progesterone increased1
Product tampering1
Product sterility lacking1
Product solubility abnormal1
Product packaging confusion1
Product package associated injury1
Product name confusion1
Product measured potency issue1
Product impurity1
Product expiration date issue1
Product dose omission in error1
Product distribution issue1
Product design issue1
Product contamination with body fluid1
Product colour issue1
Product closure removal difficult1
Product closure issue1
Product caught fire1
Procedural haemorrhage1
Procedural anxiety1
Primary hypogonadism1
Prescription form tampering1
PREMATURE MENOPAUSE1
Premature ejaculation1
Precancerous skin lesion1
Potentiating drug interaction1
Posture abnormal1
Postoperative thrombosis1
Postoperative renal failure1
Postoperative delirium1
POSTNASAL DRIP1
Posterior reversible encephalopathy syndrome1
Post procedural sepsis1
Post procedural bile leak1
Post herpetic neuralgia1
POOR QUALITY SLEEP1
Poor personal hygiene1
Polypectomy1
Polyneuropathy idiopathic progressive1
Polymyositis1
Polycystic ovaries1
Pneumonia staphylococcal1
Pneumonia klebsiella1
PNEUMONIA BACTERIAL1
Pleural thickening1
Platelet count decreased1
Plantar fasciitis1
PITUITARY TUMOUR RECURRENT1
PITUITARY HAEMORRHAGE1
Piriformis syndrome1
Physical product label issue1
Physical assault1
Photophobia1
Phlebitis deep1
Phimosis1
Pharyngitis streptococcal1
PHARYNGEAL OEDEMA1
PHARYNGEAL DISORDER1
Personality disorder1
Peroneal nerve palsy1
Peritonitis1
Perirectal abscess1
Peripheral nerve injury1
Peripheral artery stenosis1
Peripheral artery bypass1
Periarthritis1
Performance status decreased1
PENIS CARCINOMA1
Penile pain1
PENILE DISCHARGE1
Penile contusion1
PELVIC NEOPLASM1
Pelvic fracture1
Pathological fracture1
Paronychia1
PARKINSONISM1
Paraplegia1
Paranasal sinus neoplasm1
Paranasal sinus hypersecretion1
Papule1
Papilloma1
Papillary thyroid cancer1
Pancytopenia1
Pancreatitis chronic1
Pancreatic carcinoma metastatic1
Pancreatic abscess1
Pain in jaw1
Oxygen saturation1
Ovarian endometrioid carcinoma1
OVARIAN CYST1
Ovarian cancer1
Osteoporosis prophylaxis1
Osteomyelitis chronic1
Osteomyelitis1
Oscillopsia1
Orthopnoea1
Organising pneumonia1
Orchitis1
Orchidectomy1
Oral disorder1
Oral discomfort1
Optic nerve injury1
Optic nerve hypoplasia1
Optic atrophy1
OPEN WOUND1
Onychomycosis1
Onychoclasis1
Oesophageal stenosis1
Oesophageal operation1
Oesophageal carcinoma1
OEDEMA MUCOSAL1
Ocular vascular disorder1
Ocular icterus1
Ocular discomfort1
Occupational physical problem1
Occipital neuralgia1
OBSTRUCTIVE UROPATHY1
Obstructive airways disorder1
Nystagmus1
Normocytic anaemia1
NONSPECIFIC REACTION1
Nodal rhythm1
No reaction on previous exposure to drug1
Nitrite urine1
Nipple inflammation1
Neutropenia1
NEUROMA1
Nerve root compression1
NEPHROSCLEROSIS1
Nephropathy toxic1
Nephrogenic anaemia1
Nephrocalcinosis1
NEPHROBLASTOMA1
Neovascularisation1
Neoplasm skin1
NECROTISING FASCIITIS1
Neck injury1
Nasal pruritus1
Nasal oedema1
Nasal odour1
Nasal crusting1
Nasal congestion1
Nasal cavity mass1
Nail injury1
Nail hypertrophy1
NAIL GROWTH ABNORMAL1
Nail discolouration1
Myocarditis1
Myocardial injury1
Myocardial bridging1
Myeloproliferative neoplasm1
Myelopathy1
MYCOBACTERIUM TUBERCULOSIS COMPLEX TEST POSITIVE1
Mycobacterial infection1
Myasthenia gravis1
Muscle swelling1
MULTIPLE MYELOMA1
Mucous membrane disorder1
Mucinous cystadenocarcinoma of pancreas1
MOUTH ULCERATION1
Mouth breathing1
Morbid thoughts1
Monoplegia1
Monoclonal gammopathy1
Mitral valve stenosis1
Mitral valve disease1
Miliaria1
Migration of implanted drug1
Middle ear effusion1
Microangiopathy1
Microalbuminuria1
Metastatic uterine cancer1
Metastatic neoplasm1
Metastases to uterus1
Metastases to liver1
Metastases to central nervous system1
Metastases to bone marrow1
Metastases to bone1
Metastases to abdominal cavity1
Mesenteric neoplasm1
MENSTRUAL DISORDER1
MENORRHAGIA1
MENISCUS LESION1
Meningitis bacterial1
Meningitis1
MELANOCYTIC NAEVUS1
Melaena1
Medication residue present1
MEDICATION RESIDUE1
Mediastinitis1
Maternal exposure during pregnancy1
MATERNAL DRUGS AFFECTING FOETUS1
Mastitis1
Mammogram abnormal1
MALIGNANT NEOPLASM PROGRESSION1
Malignant neoplasm of spinal cord1
Macular oedema1
Macular degeneration1
Lymphocele1
Lyme disease1
LUNG NEOPLASM1
Lung consolidation1
Lung adenocarcinoma stage III1
Lumbar vertebral fracture1
Lumbar radiculopathy1
Local reaction1
Liver abscess1
Listless1
LIPOMA1
Lipids abnormal1
Lip pain1
Lip infection1
Lip exfoliation1
Limb operation1
Limb mass1
Limb deformity1
Limb asymmetry1
Ligament sprain1
Left ventricular enlargement1
LEFT VENTRICULAR END-DIASTOLIC PRESSURE INCREASED1
Learning disability1
Lead dislodgement1
Lateral medullary syndrome1
Laryngospasm1
Laryngeal oedema1
Large intestinal obstruction1
Lack of administration site rotation1
Labile hypertension1
KIDNEY INFECTION1
Jugular vein thrombosis1
Jugular vein distension1
Joint lock1
Joint effusion1
Joint destruction1
JAUNDICE NEONATAL1
Iron overload1
Iron deficiency1
Iris atrophy1
Iridotomy1
Iridectomy1
Invasive breast carcinoma1
Intraocular pressure test abnormal1
Intraocular lens implant1
Intracranial mass1
Intra-aortic balloon placement1
Intra-abdominal haematoma1
INTESTINAL OBSTRUCTION1
Intestinal infarction1
Intestinal haemorrhage1
Intervertebral disc space narrowing1
Intervertebral disc displacement1
Interventricular septum rupture1
International normalised ratio abnormal1
Internal haemorrhage1
Intermittent explosive disorder1
Intentional underdose1
Intentional dose omission1
Intellectual disability1
Instillation site odour1
Instillation site complication1
INSTILLATION SITE ABNORMAL SENSATION1
Injection site warmth1
Injection site urticaria1
Injection site nodule1
INJECTION SITE MASS1
Injection site inflammation1
Injection site haemorrhage1
INJECTION SITE HAEMATOMA1
Injection site discolouration1
Injection site abscess1
Injection related reaction1
Infrequent bowel movements1
Inferior vena cava dilatation1
Infectious pleural effusion1
Infected dermal cyst1
Increased viscosity of bronchial secretion1
Increased tendency to bruise1
Incorrect route of product administration1
Incorrect drug dosage form administered1
Incoherent1
Incisional hernia1
Incision site swelling1
Incision site infection1
Incision site haemorrhage1
Incision site erythema1
Incision site cellulitis1
Inappropriate antidiuretic hormone secretion1
Inadequate aseptic technique in use of product1
Impulse-control disorder1
Implant site scar1
Implant site paraesthesia1
Implant site oedema1
Implant site irritation1
Implant site inflammation1
Implant site induration1
Implant site discolouration1
Implant site dehiscence1
Implant site abscess1
Impaired reasoning1
Impaired quality of life1
Immunoglobulins increased1
Immune system disorder1
Immobile1
Illogical thinking1
Idiopathic urticaria1
Hysterectomy1
Hypotrichosis1
Hyposmia1
Hyporeflexia1
Hypomenorrhoea1
Hypohidrosis1
Hypogeusia1
Hypervigilance1
Hypertrophy1
HYPERTRIGLYCERIDAEMIA1
HYPERTONIC BLADDER1
HYPERTONIA1
Hypertensive nephropathy1
Hypertensive encephalopathy1
Hypertensive cardiomyopathy1
Hypertensive cardiomegaly1
Hypersexuality1
Hyperprolactinaemia1
Hyperphosphataemia1
Hypergammaglobulinaemia benign monoclonal1
Hyperandrogenism1
Hyperacusis1
Humerus fracture1
Horner's syndrome1
HOMOCYSTINAEMIA1
Histoplasmosis1
Hiccups1
Herpes simplex1
HER-2 positive breast cancer1
Hepatosplenomegaly1
HEPATOCELLULAR DAMAGE1
Hepatitis C1
Hepatitis B1
Hepatic vein thrombosis1
Hepatic vascular thrombosis1
HEPATIC RUPTURE1
HEPATIC HAEMORRHAGE1
Hepatic cancer metastatic1
Hepatic cancer1
Hemiplegic migraine1
Helicobacter gastritis1
Heat stroke1
Heart valve stenosis1
Heart valve replacement1
Heart valve operation1
Head titubation1
Head discomfort1
Hand fracture1
HALLUCINATION, VISUAL1
Hallucination, auditory1
Haemorrhoids thrombosed1
Haemorrhoidal haemorrhage1
Haemorrhoid operation1
Haemorrhagic disorder1
Haemorrhagic cerebral infarction1
Haematocrit decreased1
Haemangioma of liver1
H1N1 influenza1
Groin pain1
Gravitational oedema1
Graft thrombosis1
Gonadotrophin deficiency1
Goitre1
Glossodynia1
Glomerulonephritis rapidly progressive1
Glomerulonephritis membranous1
Glioblastoma multiforme1
Gingival swelling1
Gingival bleeding1
GINGIVAL ATROPHY1
GINGIVAL ABSCESS1
Germ cell neoplasm1
Genitals enlarged1
Genital erythema1
GENITAL CYST1
Generalised anxiety disorder1
GENE MUTATION IDENTIFICATION TEST POSITIVE1
Gastrointestinal tube insertion1
Gastrointestinal oedema1
Gastrointestinal inflammation1
Gastric polyps1
Gastric disorder1
Gastric cancer1
Gambling disorder1
Gallbladder pain1
Gallbladder operation1
Gait deviation1
Furuncle1
Fungal skin infection1
Frustration tolerance decreased1
Frequent bowel movements1
Fracture1
Formication1
Foreign body in eye1
Foot fracture1
Foot deformity1
Folliculitis1
FOCAL NODULAR HYPERPLASIA1
Flight of ideas1
Flashback1
Fistula1
Finger amputation1
FIBROCYSTIC BREAST DISEASE1
FIBRIN D DIMER INCREASED1
Femur fracture1
Feeling of relaxation1
Feeling drunk1
Feeling cold1
FEAR OF FALLING1
Fear of death1
Fascioliasis1
Fasciitis1
False positive investigation result1
Faeces pale1
Faecaloma1
FACIAL PALSY1
Eyelids pruritus1
Eyelid function disorder1
Eye swelling1
Eye injury1
Eye inflammation1
Eye infection1
Eye haemorrhage1
Eye contusion1
Extremity contracture1
EXTRAOCULAR MUSCLE PARESIS1
Extradural haematoma1
Exposure via direct contact1
Exposure to radiation1
Exposure during pregnancy1
Explorative laparotomy1
Exfoliative rash1
Exercise test abnormal1
Executive dysfunction1
Excoriation1
Exaggerated startle response1
Eunuchoidism1
Escherichia infection1
Escherichia bacteraemia1
Eructation1
Epicondylitis1
EOSINOPHILIA1
Enterobacter sepsis1
Enterobacter bacteraemia1
Enteritis1
Endocrine disorder1
Encephalomalacia1
Encephalocele1
Encephalitis1
Emphysema1
Electroencephalogram abnormal1
Electrocardiogram T wave peaked1
Electrocardiogram T wave inversion1
Electrocardiogram T wave abnormal1
Electrocardiogram ST-T segment depression1
Electrocardiogram ST segment depression1
Electrocardiogram Q wave abnormal1
Ejection fraction abnormal1
Eczema vesicular1
Ecchymosis1
Early satiety1
Ear swelling1
EAR INFECTION1
Ear disorder1
Ear discomfort1
Ear congestion1
Dysstasia1
Dyspnoea paroxysmal nocturnal1
Dysplastic naevus1
DYSPLASIA1
Dyspareunia1
Dyslexia1
Dysgraphia1
Dysaesthesia1
DUPUYTREN'S CONTRACTURE1
Dry age-related macular degeneration1
DRUG TOXICITY1
Drug eruption1
Drug effect less than expected1
Drug dispensed to wrong patient1
Drug delivery system issue1
DRUG ABUSER1
Disturbance in social behaviour1
DISTURBANCE IN SEXUAL AROUSAL1
Disseminated intravascular coagulation1
Diastolic hypertension1
Diaphragmatic paralysis1
Diabetic neuropathic ulcer1
Diabetic nephropathy1
DIABETIC COMPLICATION1
Diabetes insipidus1
Device related sepsis1
Device material issue1
Device loosening1
Device leakage1
Device failure1
Device dispensing error1
DERMATITIS EXFOLIATIVE1
Depersonalisation1
Dementia Alzheimer's type1
Deep vein thrombosis postoperative1
Decubitus ulcer1
Decreased interest1
Cytomegalovirus infection1
Cytomegalovirus chorioretinitis1
Cystic fibrosis1
Culture wound negative1
CSF myelin basic protein1
Crystal nephropathy1
Crohn's disease1
Creatinine urine increased1
Creatinine renal clearance increased1
Creatine urine increased1
Coronary vascular graft occlusion1
Coronary artery surgery1
Coronary artery aneurysm1
Corneal transplant1
Corneal oedema1
Cor pulmonale chronic1
Cor pulmonale1
Conversion disorder1
CONNECTIVE TISSUE DISORDER1
Conjunctivitis viral1
Conjunctival filtering bleb leak1
Congenital hypercoagulation1
CONGENITAL ARTERIAL MALFORMATION1
Conduction disorder1
Concussion1
Computerised tomogram coronary artery abnormal1
Compulsive shopping1
Compulsive sexual behaviour1
Compression fracture1
Complex partial seizures1
Communication disorder1
Coma scale1
Colorectal cancer1
COLON OPERATION1
COLON CANCER STAGE II1
COLON CANCER STAGE 01
Colon adenoma1
Colitis1
Cognitive linguistic deficit1
Coccidioidomycosis1
Coagulation time abnormal1
COAGULATION FACTOR XI LEVEL INCREASED1
COAGULATION FACTOR VIII LEVEL INCREASED1
Circumstance or information capable of leading to device use error1
Circumoral oedema1
Chronic myeloid leukaemia1
Chronic fatigue syndrome1
Chondropathy1
Chondromalacia1
Cholelithiasis obstructive1
Cholecystitis infective1
Cholecystectomy1
Cholangitis1
CHEST INJURY1
Chemical burn1
Change in sustained attention1
Cerebrospinal fluid leakage1
Cerebral ventricle collapse1
Cerebral small vessel ischaemic disease1
Cerebellar haematoma1
Central pain syndrome1
Central nervous system necrosis1
CAUSTIC INJURY1
Cataract operation1
Cataract nuclear1
Cartilage atrophy1
Carotid artery dissection1
CAROTID ARTERY ATHEROMA1
Cardioversion1
Cardiovascular symptom1
Cardiovascular insufficiency1
Cardiovascular event prophylaxis1
Cardiomyopathy alcoholic1
Cardiac valve prosthesis user1
Cardiac steatosis1
Cardiac septal hypertrophy1
Cardiac pacemaker battery replacement1
Cardiac output decreased1
Cardiac infection1
Cardiac fibrillation1
Cardiac ablation1
CAFE AU LAIT SPOTS1
Butterfly rash1
Bursitis1
BURNS THIRD DEGREE1
Bundle branch block1
Bronchospasm1
Bronchiolitis1
Bronchiectasis1
Breast swelling1
Breast inflammation1
Breast discharge1
Breast cancer stage I1
Brain stem haemorrhage1
Brain hypoxia1
Brain herniation1
Brain death1
Brain compression1
Brachiocephalic vein stenosis1
Brachial plexus injury1
Borderline ovarian tumour1
Bone lesion1
Bone erosion1
Bone density abnormal1
BODY TEMPERATURE DECREASED1
Body mass index increased1
Body height decreased1
Blood urine1
Blood thyroid stimulating hormone decreased1
Blood thyroid stimulating hormone abnormal1
Blood thromboplastin increased1
Blood testosterone normal1
Blood testosterone free abnormal1
BLOOD TESTOSTERONE1
Blood test abnormal1
Blood sodium increased1
Blood sodium decreased1
Blood potassium decreased1
Blood parathyroid hormone increased1
BLOOD OESTROGEN DECREASED1
Blood magnesium decreased1
BLOOD LUTEINISING HORMONE INCREASED1
Blood lactate dehydrogenase increased1
Blood iron increased1
Blood iron abnormal1
Blood homocysteine increased1
Blood heavy metal increased1
Blood heavy metal abnormal1
Blood glucose abnormal1
Blood follicle stimulating hormone increased1
BLOOD CREATINE PHOSPHOKINASE MB INCREASED1
Blood creatine phosphokinase decreased1
Blood creatine increased1
Blood cholesterol decreased1
Blood calcium increased1
BLOOD ANDROSTENEDIONE INCREASED1
Blepharitis1
BLADDER NECK OBSTRUCTION1
Bladder mass1
Biopsy prostate abnormal1
BILIARY DYSKINESIA1
BILIARY DILATATION1
Bile duct stone1
BENIGN NEOPLASM OF THYROID GLAND1
Benign neoplasm of skin1
Benign lymph node neoplasm1
BENIGN INTRACRANIAL HYPERTENSION1
Bedridden1
Basilar artery occlusion1
Bacterial test positive1
Bacterial infection1
Azotaemia1
Axillary vein thrombosis1
AUTOIMMUNE PANCREATITIS1
ATROPHY1
ATRIAL HYPERTROPHY1
Atherectomy1
Asphyxia1
ASPERMIA1
Arthritis bacterial1
Arteriovenous malformation1
Arterial rupture1
Arterial repair1
Arterial injury1
Apraxia1
Application site wound1
Application site warmth1
Application site ulcer1
Application site scab1
APPLICATION SITE PUSTULES1
APPLICATION SITE PERSPIRATION1
Application site oedema1
APPLICATION SITE NECROSIS1
Application site mass1
Application site laceration1
Application site hypoaesthesia1
Application site fissure1
APPLICATION SITE EXCORIATION1
Application site alopecia1
Apnoeic attack1
Apnoea1
Aphthous ulcer1
Aortic valve stenosis1
Aortic valve disease1
Aortic occlusion1
Antisocial personality disorder1
Anticoagulation drug level above therapeutic1
Anticoagulation drug level1
Anosognosia1
Anosmia1
Anorgasmia1
Ankle fracture1
ANGIOPLASTY1
Angiogram cerebral abnormal1
Androgen receptor gene overexpression1
Anaplastic large cell lymphoma T- and null-cell types1
Analgesic therapy1
Anal fissure1
Anal cancer1
Anaemia of chronic disease1
Anaemia macrocytic1
AMBLYOPIA1
Alpha-1 anti-trypsin deficiency1
Allergic transfusion reaction1
Alkalosis1
Aldolase increased1
Alcohol withdrawal syndrome1
Alcohol test positive1
Alcohol test false positive1
Alcohol poisoning1
Albuminuria1
Agranulocytosis1
ADVANCED SLEEP PHASE1
ADRENOCORTICAL INSUFFICIENCY ACUTE1
Adrenal neoplasm1
ADRENAL HAEMORRHAGE1
ADRENAL ADENOMA1
Administration site scar1
Administration site rash1
Administration site irritation1
Administration site hypersensitivity1
Administration site erythema1
Adjustment disorder with depressed mood1
Adenoma benign1
Adenoidectomy1
Acute stress disorder1
Acute psychosis1
Acute hepatic failure1
Acute febrile neutrophilic dermatosis1
ACTIVATED PARTIAL THROMBOPLASTIN TIME PROLONGED1
ACROMEGALY1
Acrochordon1
Acquired phimosis1
Acquired immunodeficiency syndrome1
Acquired diaphragmatic eventration1
Abscess limb1
Abnormal dreams1
Abdominal operation1
Abdominal mass1
ABDOMINAL INJURY1





Filtered ChEMBL targets:

Target UniProtKB ID Activity in nm Target Name Target gene
P02545 5623.4 Prelamin-A/C LMNA_HUMAN
P04278 0.631 Sex hormone-binding globulin SHBG_HUMAN
P10275 2.7 Androgen receptor ANDR_HUMAN
P11511 600 Aromatase CP19A_HUMAN
P16473 31.6 Thyrotropin receptor TSHR_HUMAN
Q13936 34 Voltage-dependent L-type calcium channel subunit alpha-1C CAC1C_HUMAN



Toxicity information:

Toxicity class: 6
Toxicity type: N/A
LD50: 5010 mg/kg



External links:

ChEBML: CHEMBL386630
DrugBank: DB00624